The Pet Peptide Ledger

A community research library

The pet peptide research, translated.

Peptide research on dogs, cats, and horses is some of the most interesting animal science happening right now — and almost none of it is written for owners. The Ledger reads the studies, follows the community conversations, and writes it all up in plain English.

The compound files

All compounds

Compound file · No. 01

5 min read

BPC-157

*The most-studied recovery peptide in the animal literature.* A short protein fragment modeled on a stomach protein, anchored by decades of rodent research and one well-known pharmacokinetic study in beagle dogs.

bpc-157tb-500dogscatshorses

Compound file · No. 02

5 min read

GHK-Cu

Three amino acids and a copper atom, studied since the 1980s. GHK-Cu built its reputation in skin and connective-tissue research, and the coat-quality conversation grew straight out of that work.

ghk-cudogshorses

Compound file · No. 03

5 min read

Glutathione

Every cell in your dog, cat, or horse already makes it. Researchers have spent decades asking what happens when they can't make enough.

glutathionedogscatshorses

Compound file · No. 04

5 min read

KPV

Three amino acids clipped from a hormone your pet's body already makes, and one of the more studied gut-immune peptides in the preclinical literature. Here is what the mouse colitis work actually examined, and why digestive-upset owners keep bringing it up.

kpvdogscats

Compound file · No. 05

5 min read

TB-500

*A lab-made copy of a peptide your animal's body already produces.* TB-500 is a synthetic fragment of thymosin beta-4 studied for cell migration and soft-tissue maintenance, with an unusually deep horse literature courtesy of the racing world.

tb-500bpc-157horsesdogscats

Guide · No. 02

5 min read

GHK-Cu for Skin and Coat: What the Research Suggests

The copper peptide from human plasma that became a skincare staple: what decades of Pickart-era research examined, why skin-barrier biology pulls in dog and horse people, and what to ask your vet.

ghk-cudogshorses

Guide · No. 03

5 min read

KPV and Gut Health in Cats and Dogs: The Emerging Science

A three-amino-acid fragment borrowed from the body's own calming signal has become one of the most talked-about peptides in pet-owner gut-health circles. Here is what the lab work actually shows, and what to ask your vet before the excitement runs ahead of the evidence.

kpvdogscats